Ive got a 5 year old Sarosa Comet which i isolated from his friends 3 months ago.
He has Popeye?? Both eyes are covered in what looks like a cloudy golf ball.
I treated with Melafix for a month, carrying out a 50% weekly water change.This did nothing.Then i moved onto 'Interpret anti bacterial No.9' [same water changes]....Nothing. Im now onto 'Tetra medica' General Tonic [same water changes] but im adding tonic salt at the same time.This has now also been a month.Nothing seems to work. Any ideas??
He swims around and eats fine, just cant see too good, and i dont want to put him back with the others in case the infection spreads, and he also wouldnt get his share of food.

Popeye is when the eye sticks out. If the eye is cloudy, it is probably more than just popeye. It's probably infected. I'm afraid that with something like this, it's more a matter of trial and error. You have to keep trying various antibiotics to see if one makes a difference. There are no guarantees. I always start with Maracyn I and II by Mardel which are erythromycin and minocycline and hit gram negative and positive bacteria. If the eye is really bad, it may not seem to make much difference. You can add up to a tablespoon per gallon of salt. The salt will help reduce the osmotic differential between the eye and the water. What that means is water rushes into the eye when there's more ions in the eye than the water. By adding salt, you increase the ions in the water so the eye doesn't have to work as hard to pump out water. That goes for the rest of the fish too, not just the eye. Bacteria and fungus also don't like salt so it reduces their multiplication rates. Infections like this are often caused by ubiquitous bacteria that are always in the water so if the other fish are in clean water and otherwise healthy, they probably wouldn't catch it from him. If they were previously together, they would have already been exposed anyway. You're right to keep them apart if you can though, as you say he's not going to be as good at collecting food. Goldfish also sometimes pick on the eyes of injured fish. An eye injury probably started the infection. I hope he gets better!